Erickson, Loren D.
Associate Professor, Microbiology, Immunology, and Cancer Biology
- BS, Biology, Seattle Pacific University
- PhD, Immunology, The University of Iowa
- Postdoc, Immunology, Dartmouth Medical School
PO Box 801386
Charlottesville, VA 22908
Cancer Biology, Immunology, Microbiology, Translational Science
Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus; Immunotherapeutics in the treatment of B cell disorders
- Using mouse genetics to identify the susceptibility factors that control B cell tolerance, differentiation and survival, leading to autoantibody production.
- Defining the mechanisms by which autoimmune susceptibility elicits inflammation and recruitment of innate immune cells in secondary lymphoid organs that affect B cell function.
- Examining helper activity and inflammatory cytokines of human T cells in peripheral blood of SLE patients that affect B cell function.
- Characterizing the regulation and activity in primary mouse T follicular helper cells and T follicular regulatory cells to control B cell responses.
- Defining the signal transduction events through the BCMA cytokine receptor that regulates both T follicular helper cell homeostasis and plasma cell survival in autoimmunity.
- Characterizing the development and persistence of IgE antibodies to airway allergens.