The Ubiquitin System and Human Cancer
Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics
Molecular Mechanisms of Transcriptional Regulation
Epigenetic Silencing Mechanisms-Implications in Breast Cancer and Rett Syndrome
Pathogenic mechanisms in Alzheimer's Disease and other neurodegenerative disorders
Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer
Molecular Mechanisms for Membrane Transport and Cell Signaling
Macrophage effector functions in inflammation and immunotherapy
Innate immunity, chronic disease, host-parasite interactions, Toxoplasma gondii, proteomics
Signal transduction in cancer cells
Hematopathology and Understanding the Molecular Basis of Hematopoiesis and Leukemogenesis
Molecular mechanisms controlling insulin signaling and fat synthesis.
The Role of Mitochondrial Fusion and Fission in Tumorigenesis.
Physical mechanisms of infectious disease; influenza infection; membrane fusion; antibiotic resistance; molecular dynamics simulation; machine learning.
Bacterial cell signaling, host-pathogen interactions, intestinal pathogens
Role of Prosecretory Mitogen 'Lacritin' in Epithelial Homeostasis, Secretion and Innate Defense
Role of lipid oxidation products in inflammation and vascular immunology in atherosclerosis and diabetes
Chemical biology of sphingosine 1-phosphate
Cell signaling, hematopoietic stem cell biology, molecular and epigenetic mechanisms of leukemia.
Structure-Function of Active Transporters
Nuclear Transport, Signaling, and Cancer
Apoptotic cell clearance mechanisms in health and disease
Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism and inflammation, small molecule approaches to drug discovery
Transcriptional Silencing and Aging in Yeast
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
Genome instability in cancer and repeat expansion diseases
Structure/function of integral membrane proteins; structural biophysics; enzymology and virology of ZMPSTE24; sparse-constraint structure determination; technology development