Molecular Mechanisms of Transcriptional Regulation
Pathogenic mechanisms in Alzheimer's Disease and other neurodegenerative disorders
Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer; Structural Studies of Membrane Proteins
Molecular Mechanisms for Membrane Transport and Cell Signaling
Structural biology of membrane proteins; Structure/function and structure/stability relationships and the development of new tools for protein crystallization.
Signal transduction in cancer cells
Hematopathology and Understanding the Molecular Basis of Hematopoiesis and Leukemogenesis
Transcription; Chromatin Modifications, Neurodegenerative Disease, Cancer
Molecular Mechanics of Muscle Contraction and Cell Movement
Molecular mechanisms controlling insulin signaling and fat synthesis.
The Role of Mitochondrial Fusion and Fission in Tumorigenesis.
Mechanisms of cell entry by influenza; Viral glycan recognition; drug resistance; molecular dynamics simulation; distributed computing.
Bacterial cell signaling, host-pathogen interactions, intestinal pathogens
Role of Prosecretory Mitogen 'Lacritin' in Epithelial Homeostasis, Secretion and Innate Defense
Role of lipid oxidation products in inflammation and vascular immunology in atherosclerosis and diabetes
Chemical biology of sphingosine 1-phosphate
Structure-Function of Active Transporters
Nuclear Transport, Signaling, and Cancer
Nuclear Transport in Chromatin Assembly and Transcriptional Regulation
Apoptotic cell clearance mechanisms in health and disease
Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism, atherosclerosis, Small molecule approaches to drug discovery
Transcriptional Silencing and Aging in Yeast
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
Genome instability in human disease
Structure/function of integral membrane proteins; structural biophysics; enzymology and virology of ZMPSTE24; sparse-constraint structure determination; technology development
Regulation of Gene Expression, Development and Tumor Progression by TGF beta Signaling