Molecular Mechanisms of Transcriptional Regulation
Structural and Functional Basis for Oncogenesis; Targeted Drug Development; Structural Studies of Membrane Proteins
Molecular Mechanisms for Membrane Transport and Cell Signaling
Contribution of the Inflammatory Microenvironment to Tumor Initiation, Progression and Metastasis; Molecular Mechanisms of Cancer Chemoprevention; Anti-Inflammatory Benefits of Dietary Nutrient Compounds
Structural biology of membrane proteins; Structure/function and structure/stability relationships and the development of new tools for protein crystallization.
Signal transduction in cancer cells
Hematopathology and Understanding the Molecular Basis of Hematopoiesis and Leukemogenesis
Transcription; Chromatin Modifications, Neurodegenerative Disease, Cancer
Molecular Mechanics of Muscle Contraction and Cell Movement
Molecular mechanisms controlling insulin signaling and fat synthesis.
The Role of Mitochondrial Fusion and Fission in Tumorigenesis.
Mechanisms of cell entry by influenza; Viral glycan recognition; drug resistance; molecular dynamics simulation; distributed computing.
Mechanisms used by Bacterial Pathogens to Integrate Host- and Bacterial-derived Signals to Sense their Environment, Coordinate Gene Expression, and Cause Disease
Role of Prosecretory Mitogen 'Lacritin' in Epithelial Homeostasis, Secretion and Innate Defense
Role of lipid oxidation products in inflammation and vascular immunology in atherosclerosis and diabetes
Chemical biology of sphingosine 1-phosphate
The Cause and Consequence of Somatic Mosaicism in Neurons
Structure-Function of Active Transporters
Nuclear Transport, Signaling, and Cancer
Nuclear Transport in Chromatin Assembly and Transcriptional Regulation
Apoptotic cell clearance mechanisms in health and disease
Human Immunodeficiency; Virus Gene Expression
Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism, atherosclerosis, Small molecule approaches to drug discovery
Transcriptional Silencing and Aging in Yeast
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
Genome instability in human disease
Structural biology (esp. crystallography) of integral membrane proteins; TonB-dependent active transport across the bacterial outer membrane; cancer-related membrane proteins; crystallization methods development
Regulation of Gene Expression, Development and Tumor Progression by TGF beta Signaling