Basic and translational brain tumor research
Regulation of gene expression during lymphocyte development
Ribosomal RNA transcription & processing
Signaling Pathways and Breast Cancer
Structural and Functional Basis for Oncogenesis; Targeted Drug Development; Structural Studies of Membrane Proteins
Contribution of the Inflammatory Microenvironment to Tumor Initiation, Progression and Metastasis; Molecular Mechanisms of Cancer Chemoprevention; Anti-Inflammatory Benefits of Dietary Nutrient Compounds
Tumor microenvironment and mechanisms of tumor neovascularization
Genomic Instability in Cancer Cells; Noncoding RNAs in differentiation and cancer
Neural Development; Cell Division in Neural Stem Cells; Axon Outgrowth and Guidance
Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Role of lymphatic endothelial cells in regulating immunity and self-tolerance
Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus; Immunotherapeutics in the treatment of B cell disorders
Structural biology of membrane proteins; Structure/function and structure/stability relationships and the development of new tools for protein crystallization.
Signal transduction in cancer cells
Hematopathology and Understanding the Molecular Basis of Hematopoiesis and Leukemogenesis
Transcription; Chromatin Modifications, Neurodegenerative Disease, Cancer
Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses
Spermatogenesis and oogenesis; fertilization; cancer-testis and cancer-oocyte neoantigens.
Systems-biology approaches to cancer biology and virology.
The Role of Mitochondrial Fusion and Fission in Tumorigenesis.
Human Herpes virus associated with malignancy, including Kaposi's Sarcoma
Neuronal Vulnerability: A Study of Cellular Mechanism
Involvement of the protein tyrosine phosphatase SHP-1 in signal transduction pathways
Mechanisms of Brain Astroglial Activation in Neural Injury
Molecular pathogenesis and genomic analysis of human cancers
Epigenetic Control of Perivascular and Stem Cell Plasticity/Trans-Differentiation during Injury-Repair and in Disease
Nuclear Transport, Signaling, and Cancer
Nuclear Transport in Chromatin Assembly and Transcriptional Regulation
Endothelial Phenotypes in Angiogenesis, Integrated Signaling for Microvascular Network Patterning, and Contrast Ultrasound Based Therapeutics
Apoptotic cell clearance mechanisms in health and disease
Human Immunodeficiency; Virus Gene Expression
Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism, atherosclerosis, Small molecule approaches to drug discovery
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
Molecular Mechanisms of Early Vertebrate Development and Morphogenesis. Application to Stem Cell Biology and Regenerative Medicine
Genome instability in human disease
Pathogenesis of infectious diseases and the development of new therapies and vaccines for infectious diseases and cancers.