The Ubiquitin System and Human Cancer
Basic and translational brain tumor research
Regulation of gene expression during lymphocyte development
Epigenetic Silencing Mechanisms-Implications in Breast Cancer and Rett Syndrome
Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer
Tumor microenvironment and mechanisms of tumor neovascularization
Genomic Instability in Cancer Cells; Noncoding RNAs in differentiation and cancer; Bioinformatics of cancer outcome
Macrophage effector functions in inflammation and immunotherapy
Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Tertiary lymphoid structures and intratumoral immunity
Immune mechanisms of pathogenic antibody production in allergy and autoimmunity
Signal transduction in cancer cells
Hematopathology and Understanding the Molecular Basis of Hematopoiesis and Leukemogenesis
Systems-biology approaches to cancer biology and virology.
The Role of Mitochondrial Fusion and Fission in Tumorigenesis.
Human Herpes virus associated with malignancy, including Kaposi's Sarcoma
Neuronal Vulnerability: A Study of Cellular Mechanism
Maintaining and Breaking Immune Tolerance
Identification of Novel Biomarkers for Inflammatory Myopathies
Cell signaling, hematopoietic stem cell biology, molecular and epigenetic mechanisms of leukemia.
Identification of Factors and Mechanisms that Regulate the Stability of Late Stage Atherosclerotic Lesions and the Probability of Thromboembolic Events Including a Heart Attack or Stroke
Nuclear Transport, Signaling, and Cancer
Image Guided Drug and Gene Delivery for Neurodegeneration and Cancer; Focused Ultrasound and Immunotherapy; Arteriogenesis and Angiogenesis
Apoptotic cell clearance mechanisms in health and disease
Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism and inflammation, small molecule approaches to drug discovery
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
Molecular Mechanisms of Early Vertebrate Development and Morphogenesis. Application to Stem Cell Biology and Regenerative Medicine
Genome instability in cancer and repeat expansion diseases
Pathogenesis of infectious diseases and the development of new therapies and vaccines for infectious diseases and cancers.