Basic and translational brain tumor research
Regulation of gene expression during lymphocyte development
Ribosomal RNA transcription & processing
Signaling Pathways and Breast Cancer
Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer; Structural Studies of Membrane Proteins
Tumor microenvironment and mechanisms of tumor neovascularization
Genomic Instability in Cancer Cells; Noncoding RNAs in differentiation and cancer
Neural Development; Cell Division in Neural Stem Cells; Axon Outgrowth and Guidance
Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Role of lymphatic endothelial cells in regulating immunity and self-tolerance
Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus; Immunotherapeutics in the treatment of B cell disorders
Structural biology of membrane proteins; Structure/function and structure/stability relationships and the development of new tools for protein crystallization.
Signal transduction in cancer cells
Hematopathology and Understanding the Molecular Basis of Hematopoiesis and Leukemogenesis
Transcription; Chromatin Modifications, Neurodegenerative Disease, Cancer
Systems-biology approaches to cancer biology and virology.
The Role of Mitochondrial Fusion and Fission in Tumorigenesis.
Human Herpes virus associated with malignancy, including Kaposi's Sarcoma
Neuronal Vulnerability: A Study of Cellular Mechanism
Involvement of the protein tyrosine phosphatase SHP-1 in signal transduction pathways
Identification of Novel Biomarkers for Inflammatory Myopathies
Molecular pathogenesis and genomic analysis of human cancers
Identification of Factors and Mechanisms that Regulate the Stability of Late Stage Atherosclerotic Lesions and the Probability of Thromboembolic Events Including a Heart Attack or Stroke
Nuclear Transport, Signaling, and Cancer
Nuclear Transport in Chromatin Assembly and Transcriptional Regulation
Image Guided Drug and Gene Delivery for Neurodegeneration and Cancer; Focused Ultrasound and Immunotherapy; Arteriogenesis and Angiogenesis
Apoptotic cell clearance mechanisms in health and disease
Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism, atherosclerosis, Small molecule approaches to drug discovery
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
Molecular Mechanisms of Early Vertebrate Development and Morphogenesis. Application to Stem Cell Biology and Regenerative Medicine
Genome instability in human disease
Pathogenesis of infectious diseases and the development of new therapies and vaccines for infectious diseases and cancers.