T Lymphocyte Responses To Virus Infection
Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation
Biophysical Chemistry: Membrane protein structure, function, and dynamics
Cellular and molecular mechanisms of Neisserial pathogenesis
Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Influenza, Dengue and Ebola.
Structural biology of membrane proteins; Structure/function and structure/stability relationships and the development of new tools for protein crystallization.
Molecular Mechanics of Muscle Contraction and Cell Movement
Immune regulation for HCV infection and chronic liver inflammation
Structure and Function of Bacterial Toxins: Roles in Microbial Pathogenesis and Uses in Biomedical Research
Mechanisms of cell entry by influenza; Viral glycan recognition; drug resistance; molecular dynamics simulation; distributed computing.
Human Herpes virus associated with malignancy, including Kaposi's Sarcoma
Bacterial cell signaling, host-pathogen interactions, intestinal pathogens
Involvement of the protein tyrosine phosphatase SHP-1 in signal transduction pathways
Structure-Function of Active Transporters
Immune mechanisms of defense against enteric (diarrheal) infections
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
How Viruses, Particularly Papillomaviruses, Can Cause Cancer
Pathogenesis of infectious diseases and the development of new therapies and vaccines for infectious diseases and cancers.