Student Publications
About
MSTP students are involved in a variety of research projects across Grounds. Below are the most recent first-author publications. Students’ names are bolded.
Bresticker J*, Overson DK*, Willey D, Robb F, Song AW, Truong TK, Darnell D. Numerical simulations of an integrated radio-frequency/wireless coil design for simultaneous acquisition and wireless transfer of magnetic resonance imaging data. Phys Med Biol. 2023 Jun 8;68(12):125003. doi: 10.1088/1361-6560/acd614. PMID: 37192635; PMCID: PMC10251249.
Dutta AB., Lank DS., Przanowska RK., Przanowski P., Wang L., Nguyen B., Walavalkar NM., Duarte FM., Guertin MJ. (2023). Kinetic networks identify TWIST2 as a key regulatory node in adipogenesis. Genome Research. 33, 314-331. PMCID: PMC10078291
Towers EB, Sentaro B, Lynch WJ (2023). Estradiol Enhances the Development of Addiction-Like Features in a Female Rat Model of Opioid Use Disorder. Special Edition, Neuroendocrinology: The Role of Hormones in Substance Use Disorders. PMID: 36878201.
Wilson, Briana, Zhangli Su, Pankaj Kumar, Anindya Dutta. 2023. “XRN2 suppresses aberrant entry of tRNA trailers into argonaute in humans and Arabidopsis.” PLoS Genet 19(5): e1010755. https://doi.org/10.1371/journal.pgen.1010755
Cochran J, Yura Y, Thel MC, Doviak H, Polizio AH, Arai Y, Arai Y, Horitani K, Park E, Chavkin NW, Kour A, Sano S, Mahajan N, Evans M, Huba M, Naya NM, Sun H, Ban Y, Hirschi KK, Toldo S, Abbate A, Druley TE, Ruberg FL, Maurer MS, Ezekowitz JA, Dyck JRB, Walsh K. Clonal Hematopoiesis in Clinical and Experimental Heart Failure With Preserved Ejection Fraction. Circulation. 2023 Sep 8. doi: 10.1161/CIRCULATIONAHA.123.064170. Epub ahead of print. PMID: 37681311
Cheon H, Elghawy O, Shemo BC, Feith DJ, Loughran TP. LGL leukemia patients exhibit substantial protective humoral responses following SARS-CoV-2 vaccination. eJHaem. 2022;3(3):919-923. doi:10.1002/jha2.472
Comlekoglu, T., V. Kumar, K. King, H. Al-Saif, R. Li, and N. Couser. “Ophthalmic abnormalities in Wieacker-Wolff syndrome.” Journal of American Association for Pediatric Ophthalmology and Strabismus. (2022). PMID: 35121145
Kovacs MA, Cowan MN, Babcock IW, Sibley LA, Still K, Batista SJ, Labuzan SA, Sethi I, Harris TH. Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain. Elife. 2022 Dec 21;11:e80775. doi: 10.7554/eLife.80775. PMID: 36541708; PMCID: PMC9812409.
Kraichely KN, Clinkscales SM, Hendy CM, Mendoza E, Parnham SR, and MW Giuliano. (2022) Minimal Increments of Hydrophobic Collapse in the N-terminus of the Neuropeptide Galanin. Biochemistry, 61(12), 1151-1166.
Mangalmurti, Aman: How neurons die in Alzheimer’s disease: Implications for neuroinflammation (2022) PMCID: PMC35691251
Mulligan RJ, Yap CC, Winckler B. Endosomal transport to lysosomes and the TGN in neurons: visualizing maturational flux, Golgi: Methods and Protocol, 2022. PMID: 36512240
Pattarabanjird, T., Marshall, M., Upadhye, A., Srikakulapu, P., Garmey, J., Haider, A., Taylor, A.M., Lutgens, E. and McNamara, C.A. “B-1b Cells Possess Unique bHLH-Driven P62-Dependent Self-Renewal and Atheroprotection.” Circulation research vol. 130,7 (2022): 981-993. doi:10.1161/CIRCRESAHA.121.320436
Sessions DT, Kim KB, Kashatus JA, Churchill N, Park KS, Mayo MW, Sesaki H, Kashatus DF. Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma. Cell Rep. 2022 Dec 13;41(11):111818. doi: 10.1016/j.celrep.2022.111818. PMID: 36516772.
Towers EB, Kilgore M, Bakhti-Suroosh A, Pidaparthi L, Williams IL, Abel JM, Lynch WJ (2022). Sex Differences in the Neuroadaptations Associated with Incubated Cocaine-Craving: A Focus on the Dorsomedial Prefrontal Cortex. Frontiers of Behavioral Neuroscience, PMID: 36688133.
Towers EB, Sentaro B, Lynch WJ (2022). Invited Manuscript: Sex- and Dose-Dependent Differences in the Development of an Addiction-Like Phenotype Following Extended-Access Fentanyl Self-Administration. Special Edition, Frontiers of Pharmacology: Unraveling Vulnerability Factors in Addiction, Drug Use, and Potential Treatments, PMID: 35370634.
White III Z, Elagib KE, Gru AA, Goldfarb AN. Liver kinase B1 (LKB1) in murine erythroid progenitors modulates erythropoietin setpoint in association with maturation control. Blood Cells Mol Dis. 2022 Jun 11;97:102688. doi: 10.1016/j.bcmd.2022.102688. Epub ahead of print. PMID: 35717902.
Ma WF, Hodonsky CJ, Turner AW, Wong D, Song Y, Mosquera JV, Ligay AV, Slenders L, Gancayco C, Pan H, Barrientos NB, Mai D, Alencar GF, Owsiany K, Owens GK, Reilly MP, Li M, Pasterkamp G, Mokry M, van der Laan SW, Khomtchouk BB, Miller CL. Enhanced single-cell RNA-seq workflow reveals coronary artery disease cellular cross-talk and candidate drug targets. Atherosclerosis. 2021 Nov 26;340:12-22. doi: 10.1016/j.atherosclerosis.2021.11.025. Epub ahead of print. PMID: 34871816.
Towers, EB, & Lynch, W. J. (2021). The importance of examining sex differences in animal models validated to induce an addition-like phenotype. Pharmacology, Biochemistry, and Behavior, 173255-173255.
Suzich JB, Cuddy SR, Baidas H, Dochnal S, Ke E, Schinlever AR, Babnis A, Boutell C, Cliffe AR. PML-NB-dependent type I interferon memory results in a restricted form of HSV latency. EMBO Rep. 2021 Jul 1:e52547. doi: 10.15252/embr.202152547. Epub ahead of print. PMID: 34197022.
Towers EB, Bakhti-Suroosh A, Lynch WJ. Females develop features of an addiction-like phenotype sooner during withdrawal than males. Psychopharmacology (Berl). 2021 Apr 27. doi: 10.1007/s00213-021-05846-3. Epub ahead of print. PMID: 33907871.
Bakhti-Suroosh A, Towers EB, Lynch WJ. A buprenorphine-validated rat model of opioid use disorder optimized to study sex differences in vulnerability to relapse. Psychopharmacology (Berl). 2021 Apr;238(4):1029-1046. doi: 10.1007/s00213-020-05750-2. Epub 2021 Jan 6. PMID: 33404740; PMCID: PMC7786148.
ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels. Elife. 2021 Jan 7;10. doi: 10.7554/eLife.64787.
Chatrath A, Ratan A, Dutta A. Germline Variants That Affect Tumor Progression. Trends Genet. 2020 Nov 14:S0168-9525(20)30294-8. doi: 10.1016/j.tig.2020.10.005. Epub ahead of print. PMID: 33203571.
HIV-cell membrane fusion intermediates are restricted by Serincs as revealed by cryo-electron and TIRF microscopy. J Biol Chem. 2020 Nov 6;295(45):15183-15195. doi: 10.1074/jbc.RA120.014466.
Starting Conversations toward Inclusion. Cell. 2020 Oct 29;183(3):583-586. doi: 10.1016/j.cell.2020.09.003. PubMed PMID: 33125885.
Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis. Nat Commun. 2020 Sep 10;11(1):4524. doi: 10.1038/s41467-020-18113-4.
Nonlinearities between inhibition and T-type calcium channel activity bidirectionally regulate thalamic oscillations. Elife. 2020 Sep 9;9. doi: 10.7554/eLife.59548.
Computational model predicts paracrine and intracellular drivers of fibroblast phenotype after myocardial infarction. Matrix Biol. 2020 Sep;91-92:136-151. doi: 10.1016/j.matbio.2020.03.007.
The Ethanolamine-Sensing Transcription Factor EutR Promotes Virulence and Transmission during Citrobacter rodentium Intestinal Infection. Infect Immun. 2020 Aug 19;88(9). doi: 10.1128/IAI.00137-20.
Khan, A.K., Jagielnicki, M., McIntire, W.E., Purdy, M.D., Dharmarajan, V. Griffin, P.R., Yeager M. A Steric “Ball-and-Chain” Mechanism for pH-Mediated Regulation of Gap Junction Channels. Cell Reports 2020, 31(3): 107482.
Chatrath A, Przanowska R, Kiran S, Su Z, Saha S, Wilson B, Tsunematsu T, Ahn J-H, Lee KY, Paulsen T, Sobierajska E, Kiran M, Tang X, Li T, Kumar P, Ratan A, Dutta A. 2020. The pan-cancer landscape of prognostic germline variants in 10,582 patients. Genome Medicine 12:15. doi:10.1186/s13073-020-0718-7
Cheon H, Dziewulska KH, Moosic KB, Olson KC, Gru AA, Feith DJ, Loughran TP. 2020. Advances in the Diagnosis and Treatment of Large Granular Lymphocytic Leukemia. Curr Hematol Malig Rep. doi:10.1007/s11899-020-00565-6
Kozlowski MM, Rudolf MA, Corwin JT. 2020. EGF and a GSK3 Inhibitor Deplete Junctional E-cadherin and Stimulate Proliferation in the Mature Mammalian Ear. J Neurosci 40:2618–2632. doi:10.1523/JNEUROSCI.2630-19.2020
Lammert CR, Frost EL, Bellinger CE, Bolte AC, McKee CA, Hurt ME, Paysour MJ, Ennerfelt HE, Lukens JR. 2020. AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment. Nature 1–6. doi:10.1038/s41586-020-2174-3
LeBlanc FR, Pearson JM, Tan S-F, Cheon H, Xing JC, Dunton W, Feith DJ, Loughran TP. n.d. Sphingosine kinase-2 is overexpressed in large granular lymphocyte leukaemia and promotes survival through Mcl-1. British Journal of Haematology n/a. doi:10.1111/bjh.16530
Podyma B, Johnson D-A, Sipe L, Remcho TP, Battin K, Liu Y, Yoon SO, Deppmann CD, Güler AD. n.d. The p75 neurotrophin receptor in AgRP neurons is necessary for homeostatic feeding and food anticipation. eLife 9. doi:10.7554/eLife.52623
Saha S, Kiran M, Kuscu C, Chatrath A, Wotton D, Mayo MW, Dutta A. 2020. Long Noncoding RNA DRAIC Inhibits Prostate Cancer Progression by Interacting with IKK to Inhibit NF-κB Activation. Cancer Res 80:950–963. doi:10.1158/0008-5472.CAN-19-3460
Michel N, Majumdar UB, Lannigan J, McConnell MJ. Imaging Flow Cytometry Quantifies Neural Genome Dynamics. Cytometry A. 2019 May 7. doi: 10.1002/cyto.a.23783. [Epub ahead of print] PubMed PMID: 31063256.
Paul AGA, Muehling LM, Eccles JD, Woodfolk JA. T cells in severe childhood asthma. Clin Exp Allergy. 2019 May;49(5):564-581. doi: 10.1111/cea.13374. Epub 2019 Apr 4. Review. PubMed PMID: 30793397; PubMed Central PMCID: PMC6488378.
Owsiany KM, Alencar GF, Owens GK. Revealing the Origins of Foam Cells in Atherosclerotic Lesions. Arterioscler Thromb Vasc Biol. 2019 May;39(5):836-838. doi: 10.1161/ATVBAHA.119.312557. PubMed PMID: 31017823; PubMed Central PMCID: PMC6482855.
Kamata T, Yang CS, Jividen K, Spencer A, Dworak N, Oostdyk LT, Paschal BM. Detection of ADP-Ribosylation of the Androgen Receptor Using the Recombinant Macrodomain AF1521 from Archaeoglobus fulgidus. Methods Mol Biol. 2019;1966:107-124. doi: 10.1007/978-1-4939-9195-2_9. PubMed PMID: 31041742.
Paysour MJ, Bolte AC, Lukens JR. Crosstalk Between the Microbiome and Gestational Immunity in Autism-Related Disorders. DNA Cell Biol. 2019 May;38(5):405-409. doi: 10.1089/dna.2019.4653. Epub 2019 Feb 28. PubMed PMID: 30817175.
Singh S, Wang L, Schaff DL, Sutcliffe MD, Koeppel AF, Kim J, Onengut-Gumuscu S, Park KS, Zong H, Janes KA. In situ 10-cell RNA sequencing in tissue and tumor biopsy samples. Sci Rep. 2019 Mar 20;9(1):4836. doi: 10.1038/s41598-019-41235-9. PubMed PMID: 30894605; PubMed Central PMCID: PMC6426952.
Szymura SJ, Zaemes JP, Allison DF, Clift SH, D’Innocenzi JM, Gray LG, McKenna BD, Morris BB, Bekiranov S, LeGallo RD, Jones DR, Mayo MW. NF-κB upregulates glutamine-fructose-6-phosphate transaminase 2 to promote migration in non-small cell lung cancer. Cell Commun Signal. 2019 Mar 18;17(1):24. doi: 10.1186/s12964-019-0335-5. PubMed PMID: 30885209; PubMed Central PMCID: PMC6421657.
Harbom LJ, Rudisill TL, Michel N, Litwa KA, Beenhakker MP, McConnell MJ. The effect of rho kinase inhibition on morphological and electrophysiological maturity in iPSC-derived neurons. Cell Tissue Res. 2019 Mar;375(3):641-654. doi: 10.1007/s00441-018-2942-7. Epub 2018 Nov 8. PubMed PMID: 30406823.
Hess DL, Kelly-Goss MR, Cherepanova OA, Nguyen AT, Baylis RA, Tkachenko S, Annex BH, Peirce SM, Owens GK. Perivascular cell-specific knockout of the stem cell pluripotency gene Oct4 inhibits angiogenesis. Nature Communications. 2019 Feb 27;10(1):967. doi: 10.1038/s41467-019-08811-z. PubMed PMID: 30814500; PubMed Central PMCID: PMC6393549.
Rosen DA, Seki SM, Fernández-Castañeda A, Beiter RM, Eccles JD, Woodfolk JA, Gaultier A. Modulation of the sigma-1 receptor-IRE1 pathway is beneficial in preclinical models of inflammation and sepsis. Sci Transl Med. 2019 Feb 6;11(478). pii: eaau5266. doi: 10.1126/scitranslmed.aau5266. Erratum in: Sci Transl Med. 2019 Mar 27;11(485):. PubMed PMID: 30728287.
Little JN, Dwyer ND. p53 deletion rescues lethal microcephaly in a mouse model with neural stem cell abscission defects. Human Molecular Genetics. 2019 Feb 1;28(3):434-447. doi: 10.1093/hmg/ddy350. PubMed PMID: 30304535; PubMed Central. PMCID: PMC6337704.
Rowley CA, Kendall MM. To B12 or not to B12: Five questions on the role of cobalamin in host-microbial interactions. PLoS Pathog. 2019 Jan 3;15(1):e1007479. doi: 10.1371/journal.ppat.1007479. eCollection 2019 Jan. Review. PubMed PMID: 30605490; PubMed Central PMCID: PMC6317780.
Rowley CA, Anderson CJ, Kendall MM. Ethanolamine Influences Human Commensal Escherichia coli Growth, Gene Expression, and Competition with Enterohemorrhagic E. coli O157:H7. MBio. 2018 Oct 2;9(5). pii: e01429-18. doi: 10.1128/mBio.01429-18. PubMed PMID: 30279284; PubMed Central PMCID: PMC6168858.
Cortina GA, Kasson PM. Predicting allostery and microbial drug resistance with molecular simulations. Curr Opin Struct Biol. 2018 Oct;52:80-86. doi: 10.1016/j.sbi.2018.09.001. Epub 2018 Sep 19. Review. PubMed PMID: 30243041; PubMed Central PMCID: PMC6296865.
Reon BJ, Takao Real Karia B, Kiran M, Dutta A. LINC00152 Promotes Invasion through a 3′-Hairpin Structure and Associates with Prognosis in Glioblastoma. Mol Cancer Res. 2018 Oct;16(10):1470-1482. doi: 10.1158/1541-7786.MCR-18-0322. Epub 2018 Jul 10. PubMed PMID: 29991527; PubMed Central PMCID: PMC6170721.
Gomez D, Baylis RA, Durgin BG, Newman AAC, Alencar GF, Mahan S, St Hilaire C, Müller W, Waisman A, Francis SE, Pinteaux E, Randolph GJ, Gram H, Owens GK. Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice. Nat Med. 2018 Sep;24(9):1418-1429. doi: 10.1038/s41591-018-0124-5. Epub 2018 Jul 23. PubMed PMID: 30038218; PubMed Central PMCID: PMC6130822.
Suzich JB, Cliffe AR. Strength in diversity: Understanding the pathways to herpes simplex virus reactivation. Virology. 2018 Sep;522:81-91. doi: 10.1016/j.virol.2018.07.011. Epub 2018 Jul 14. Review. PubMed PMID: 30014861; PubMed Central PMCID: PMC6092753.
Anderson MR, Pleet ML, Enose-Akahata Y, Erickson J, Monaco MC, Akpamagbo Y, Velluci A, Tanaka Y, Azodi S, Lepene B, Jones J, Kashanchi F, Jacobson S. Viral antigens detectable in CSF exosomes from patients with retrovirus associated neurologic disease: functional role of exosomes. Clin Transl Med. 2018 Aug 27;7(1):24. doi: 10.1186/s40169-018-0204-7. PubMed PMID: 30146667; PubMed Central PMCID: PMC6110307.
Newman AA, Baylis RA, Hess DL, Griffith SD, Shankman LS, Cherepanova OA, Owens GK. Irradiation abolishes smooth muscle investment into vascular lesions in specific vascular beds. JCI Insight. 2018 Aug 9;3(15). pii: 121017. doi: 10.1172/jci.insight.121017. eCollection 2018 Aug 9. PubMed PMID: 30089722; PubMed Central PMCID: PMC6129122.
Sharma AK, Charles EJ, Zhao Y, Narahari AK, Baderdinni PK, Good ME, Lorenz UM, Kron IL, Bayliss DA, Ravichandran KS, Isakson BE, Laubach VE. Pannexin-1 channels on endothelial cells mediate vascular inflammation during lung ischemia-reperfusion injury. Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L301-L312. doi: 10.1152/ajplung.00004.2018. Epub 2018 May 10. PubMed PMID: 29745255; PubMed Central PMCID: PMC6139659.
Lammert CR, Frost EL, Bolte AC, Paysour MJ, Shaw ME, Bellinger CE, Weigel TK, Zunder ER, Lukens JR. Cutting Edge: Critical Roles for Microbiota-Mediated Regulation of the Immune System in a Prenatal Immune Activation Model of Autism. J Immunol. 2018 Aug 1;201(3):845-850. doi: 10.4049/jimmunol.1701755. Epub 2018 Jul 2. PubMed PMID: 29967099; PubMed Central PMCID: PMC6057827.
Bolte AC, Lukens JR. Th17 Cells in Parkinson’s Disease: The Bane of the Midbrain. Cell Stem Cell. 2018 Jul 5;23(1):5-6. doi: 10.1016/j.stem.2018.06.016. PubMed PMID: 29979991.
Seki SM, Stevenson, M, Rosen, AM, Arandjelovic, S, Gemta, L, Bullock T, Gaultier, A. Lineage-specific metabolic properties and vulnerabilities of T cells in the demyelinating central nervous system. J Immunol. 2018 Jun 15. doi: 10.4049/jimmunol.1600825. PMID: 28507026
Stevens JS, Gray MC, Morisseau C, Criss AK. Endocervical and Neutrophil Lipoxygenases Coordinate Neutrophil Transepithelial Migration to Neisseria Gonorrhoeae. Journal of Infectious Diseases. 2018 Jun 13. doi: 10.1093/infdis/jiy347. PMID: 29905822
Wisniewski JA, Muehling LM, Eccles JD, Capaldo BJ, Agrawal R, Shirley DA, Patrie JT, Workman LJ, Schuyler AJ, Lawrence MG, Teague WG, Woodfolk JA. T(H)1 signatures are present in the lower airways of children with severe asthma, regardless of allergic status. J Allergy Clin Immunol. 2018 Jun;141(6):2048-2060.e13. doi: 10.1016/j.jaci.2017.08.020. Epub 2017 Sep 20.
PubMed PMID: 28939412; PubMed Central PMCID: PMC5860937.
Adamson SE, Polanowska-Grabowska R, Marqueen K, Griffiths R, Angdisen J, Breevoort SR, Schulman IG, Leitinger N. Deficiency of Dab2 (Disabled Homolog 2) in Myeloid Cells Exacerbates Inflammation in Liver and Atherosclerotic Plaques in LDLR (Low-Density Lipoprotein Receptor)-Null Mice-Brief Report. Arterioscler Thromb Vasc Biol. 2018 May;38(5):1020-1029. doi: 10.1161/ATVBAHA.117.310467. Epub 2018 Mar 29. PubMed PMID: 29599136; PubMed Central PMCID: PMC5920703.
Anderson M, Kashanchi F, Jacobson S. Role of Exosomes in Human Retroviral Mediated Disorders. J Neuroimmune Pharmacol. 2018 Apr 14. doi: 10.1007/s11481-018-9784-7. PMID: 29656370
Cronk JC, Filiano AJ, Louveau A, Marin I, Marsh R, Ji E, Goldman DH, Smirnov I, Geraci N, Acton S, Overall CC, Kipnis J. Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia. J Exp Med. 2018 Apr 11. pii: jem.20180247. doi: 10.1084/jem.20180247. PMID: 29643186
Cortina GA, Hays JM, Kasson PM. Conformational Intermediate That Controls KPC-2 Catalysis and Beta-Lactam Drug Resistance. ACS Catal. 2018 Apr 6;8(4):2741-2747. doi: 10.1021/acscatal.7b03832. Epub 2018 Feb 21. PubMed PMID: 30637173; PubMed Central PMCID: PMC6324736.
Carlton AL, Illendula A, Gao Y, Llaneza DC, Boulton A, Shah A, Rajewski RA, Landen CN, Wotton D, Bushweller JH. Small molecule inhibition of the CBFβ/RUNX interaction decreases ovarian cancer growth and migration through alterations in genes related to epithelial-to-mesenchymal transition. Gynecol Oncol. 2018 Mar 15. pii: S0090-8258(18)30174-4. doi: 10.1016/j.ygyno.2018.03.005. PMID: 29551565
Adamson SE, Montgomery G, Seaman SA, Peirce-Cottler SM, Leitinger N. Myeloid P2Y2 receptor promotes acute inflammation but is dispensable for chronic high-fat diet-induced metabolic dysfunction. Purinergic Signal. 2018 Mar;14(1):19-26. doi: 10.1007/s11302-017-9589-9. Epub 2017 Oct 30. PubMed PMID: 29086245; PubMed Central PMCID: PMC5842150.
Gilchrist CA, Cotton JA, Burkey C, Arju T, Gilmartin A, Lin Y, Ahmed E, Steiner K, Alam M, Ahmed S, Robinson G, Zaman SU, Kabir M, Sanders M, Chalmers RM, Ahmed T, Ma JZ, Haque R, Faruque ASG, Berriman M, Petri WA Jr. Genetic diversity of Cryptosporidium hominis in a Bangladeshi community as revealed by whole genome sequencing. J Infect Dis. 2018 Mar 5. doi: 10.1093/infdis/jiy121. PMID: 29514308
Maqani N, Fine RD, Shahid M, Li M, Enriquez-Hesles E, Smith JS. Spontaneous mutations in CYC8 and MIG1 suppress the short chronological lifespan of budding yeast lacking SNF1/AMPK. Microb Cell. 2018 Feb 19;5(5):233-248. doi: 10.15698/mic2018.05.630. PubMed PMID: 29796388; PubMed Central PMCID: PMC5961917.
Penberthy KK, Lysiak JJ, Ravichandran KS. Rethinking Phagocytes: Clues from the Retina and Testes. Trends Cell Biol. 2018 Feb 14. pii: S0962-8924(18)30004-7. doi: 10.1016/j.tcb.2018.01.004. PMID: 2945466
Klein PM, Lu AC, Harper ME, McKown HM, Morgan JD, Beenhakker MP. Tenuous Inhibitory GABAergic Signaling in the Reticular Thalamus. J Neurosci. 2018 Jan 31;38(5):1232-1248. doi: 10.1523/JNEUROSCI.1345-17.2017. Epub 2017 Dec 22. PubMed PMID: 29273603; PubMed Central PMCID: PMC5792478.
Stevens JS, Criss AK. Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract: neutrophilic host response, sustained infection, and clinical sequelae. Curr Opin Hematol. 2018 Jan;25(1):13-21. doi: 10.1097/MOH.0000000000000394. Review. PubMed PMID: 29016383; PubMed Central PMCID: PMC5753798.
Harbom LJ, Michel N, McConnell MJ. Single-cell analysis of diversity in human stem cell-derived neurons. Cell Tissue Res. 2018 Jan;371(1):171-179. doi: 10.1007/s00441-017-2728-3. Epub 2017 Nov 29. Review. PubMed PMID: 29185070; PubMed Central PMCID: PMC6260820.
Khalil S, Delehanty L, Grado S, Holy M, White Z 3rd, Freeman K, Kurita R, Nakamura Y, Bullock G, Goldfarb A. Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor. J Exp Med. 2017 Dec 27. pii: jem.20170396. doi: 10.1084/jem.20170396. PMID: 29282252
Gilmartin AA, Petri WA Jr. Exploring the mechanism of amebic trogocytosis: therole of amebic lysosomes. Microb Cell. 2017 Dec 6;5(1):1-3. doi: 10.15698/mic2018.01.606. PubMed PMID: 29354646; PubMed Central PMCID: PMC5772035.
Seki SM, Gaultier A. Exploring Non-Metabolic Functions of Glycolytic Enzymes in Immunity. Front Immunol. 2017 Nov 22;8:1549. doi: 10.3389/fimmu.2017.01549. eCollection 2017. Review. PMID: 29213268
Penberthy KK, Rival C, Shankman LS, Raymond MH, Zhang J, Perry JSA, Lee CS, Han CZ, Onengut-Gumuscu S, Palczewski K, Lysiak JJ, Ravichandran KS. Context-dependent compensation among phosphatidylserine-recognition receptors. Sci Rep. 2017 Nov 7;7(1):14623. doi: 10.1038/s41598-017-15191-1. PMID: 29116131
Baylis RA, Gomez D, Mallat Z, Pasterkamp G, Owens GK. The CANTOS Trial: One Important Step for Clinical Cardiology but a Giant Leap for Vascular Biology. Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):e174-e177. doi: 10.1161/ATVBAHA.117.310097. Epub 2017 Sep 28. PubMed PMID: 28970294; PubMed Central PMCID: PMC5685554.
Shim JV, Chun B, van Hasselt JGC, Birtwistle MR, Saucerman JJ, Sobie EA. Mechanistic Systems Modeling to Improve Understanding and Prediction of Cardiotoxicity Caused by Targeted Cancer Therapeutics. Front Physiol. 2017 Sep 8;8:651. doi: 10.3389/fphys.2017.00651. eCollection 2017. PubMed PMID: 28951721; PubMed Central PMCID: PMC5599787.
Latallo MJ, Cortina GA, Faham S, Nakamoto RK, Kasson PM. Predicting allosteric mutants that increase activity of a major antibiotic resistance enzyme. Chem Sci. 2017 Sep 1;8(9):6484-6492. doi: 10.1039/c7sc02676e. Epub 2017 Jul 19. PubMed PMID: 28989673; PubMed Central PMCID: PMC5628580.
Gilmartin AA, Ralston KS, Petri WA Jr. Inhibition of Amebic Lysosomal Acidification Blocks Amebic Trogocytosis and Cell Killing. MBio. 2017 Aug 29;8(4). pii: e01187-17. doi: 10.1128/mBio.01187-17. PMID: 28851845
Khalil S, Holy M, Grado S, Fleming R, Kurita R, Nakamura Y, Goldfarb A. A specialized pathway for erythroid iron delivery through lysosomal trafficking of transferrin receptor 2. Blood Adv. 2017 Jun 27;1(15):1181-1194. doi: 10.1182/bloodadvances.2016003772. eCollection 2017 Jun 27. PMID: 29296759
Elagib KE, Lu CH, Mosoyan G, Khalil S, Zasadzińska E, Foltz DR, Balogh P, Gru AA, Fuchs DA, Rimsza LM, Verhoeyen E, Sansó M, Fisher RP, Iancu-Rubin C, Goldfarb AN. Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition. J Clin Invest. 2017 Jun 1;127(6):2365-2377. doi: 10.1172/JCI88936. Epub 2017 May 8. PubMed PMID: 28481226; PubMed Central PMCID: PMC5451240.
Filiano AJ, Gadani SP, Kipnis J. How and why do T cells and their derived cytokines affect the injured and healthy brain? Nat Rev Neurosci. 2017 Jun;18(6):375-384. doi: 10.1038/nrn.2017.39. Epub 2017 Apr 27. Review. PubMed PMID: 28446786; PubMed Central PMCID: PMC5823005.
Nagdas S, Kashatus DF. The Interplay between Oncogenic Signaling Networks and Mitochondrial Dynamics. Antioxidants (Basel). 2017 May 17;6(2). pii: E33. doi: 10.3390/antiox6020033. Review. PubMed PMID: 28513539; PubMed Central PMCID: PMC5488013.
McNeely KC, Cupp TD, Little JN, Janisch KM, Shrestha A, Dwyer ND. Mutation of Kinesin-6 Kif20b causes defects in cortical neuron polarization and morphogenesis. Neural Dev. 2017 Mar 31;12(1):5. doi: 10.1186/s13064-017-0082-5. PubMed PMID: 28359322; PubMed Central PMCID: PMC5374676.
Baylis RA, Gomez D, Owens GK. Shifting the Focus of Preclinical, Murine Atherosclerosis Studies From Prevention to Late-Stage Intervention. Circ Res. 2017 Mar 3;120(5):775-777. doi: 10.1161/CIRCRESAHA.116.310101. PubMed PMID: 28254801; PubMed Central PMCID: PMC5338643.
Weaver JL, Arandjelovic S, Brown G, K Mendu S, S Schappe M, Buckley MW, Chiu YH, Shu S, Kim JK, Chung J, Krupa J, Jevtovic-Todorovic V, Desai BN, Ravichandran KS, Bayliss DA. Hematopoietic pannexin 1 function is critical for neuropathic pain. Sci Rep. 2017 Feb 14;7:42550. doi: 10.1038/srep42550. PubMed PMID: 28195232; PubMed Central PMCID: PMC5307344.
Gadani SP, Smirnov I, Smith AT, Overall CC, Kipnis J. Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury. J Exp Med. 2017 Feb;214(2):285-296. doi: 10.1084/jem.20161982. Epub 2016 Dec 19. PubMed PMID: 27994070; PubMed Central PMCID: PMC5294864.
Cronk JC, Herz J, Kim TS, Louveau A, Moser EK, Sharma AK, Smirnov I, Tung KS, Braciale TJ, Kipnis J. Influenza A induces dysfunctional immunity and death in MeCP2-overexpressing mice. JCI Insight. 2017 Jan 26;2(2):e88257. doi: 10.1172/jci.insight.88257. PubMed PMID: 28138553; PubMed Central PMCID: PMC5256138.
Krueger PD, Narayanan S, Surette FA, Brown MG, Sung SJ, Hahn YS. Murine liver-resident group 1 innate lymphoid cells regulate optimal priming of anti-viral CD8+ T cells. J Leukoc Biol. 2017 Jan;101(1):329-338. doi: 10.1189/jlb.3A0516-225R. Epub 2016 Aug 4. PubMed PMID: 27493244.
Reon BJ, Anaya J, Zhang Y, Mandell J, Purow B, Abounader R, Dutta A. Expression of lncRNAs in Low-Grade Gliomas and Glioblastoma Multiforme: An In Silico Analysis. PLoS Med. 2016 Dec 6;13(12):e1002192. doi: 10.1371/journal.pmed.1002192. eCollection 2016 Dec. PubMed PMID: 27923049; PubMed Central PMCID: PMC5140055.
Cortina GA, Kasson PM. Excess positional mutual information predicts both local and allosteric mutations affecting beta lactamase drug resistance. Bioinformatics. 2016 Nov 15;32(22):3420-3427. Epub 2016 Jul 27. PubMed PMID: 27466622; PubMed Central PMCID: PMC6078173.
Cronk JC, Derecki NC, Litvak V, Kipnis J. Unexpected cellular players in Rett syndrome pathology. Neurobiol Dis. 2016 Aug;92(Pt A):64-71. doi: 10.1016/j.nbd.2015.05.005. Epub 2015 May 14. Review. PMID: 25982834
Chuang TY, Guo Y, Seki SM, Rosen AM, Johanson DM, Mandell JW, Lucchinetti CF, Gaultier A. LRP1 expression in microglia is protective during CNS autoimmunity. Acta Neuropathol Commun. 2016 Jul 11;4(1):68. doi: 10.1186/s40478-016-0343-2. PubMed PMID: 27400748; PubMed Central PMCID: PMC4940960
Anderson MR, Kashanchi F, Jacobson S. Exosomes in Viral Disease. Neurotherapeutics. 2016 Jul;13(3):535-46. doi: 10.1007/s13311-016-0450-6. PubMed PMID: 27324390; PubMed PMCID: PMC4965413
Narayanan S, Nieh AH, Kenwood BM, Davis CA, Tosello-Trampont AC, Elich TD, Breazeale SD, Ward E, Anderson RJ, Caldwell SH, Hoehn KL, Hahn YS. Distinct Roles for Intracellular and Extracellular Lipids in Hepatitis C Virus Infection. PLoS One. 2016 Jun 9;11(6):e0156996. doi: 10.1371/journal.pone.0156996. eCollection2016. PubMed PMID: 27280294; PubMed Central PMCID: PMC4900644
Cherepanova OA, Gomez D, Shankman LS, Swiatlowska P, Williams J, Sarmento OF, Alencar GF, Hess DL, Bevard MH, Greene ES, Murgai M, Turner SD, Geng YJ, Bekiranov S, Connelly JJ, Tomilin A, Owens GK. Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective. Nat Med. 2016 Jun;22(6):657-65. doi: 10.1038/nm.4109. Epub 2016 May 16. PubMed PMID: 27183216; PubMed Central PMCID: PMC4899256.
Zeigler AC, Richardson WJ, Holmes JW, Saucerman JJ. A computational model of cardiac fibroblast signaling predicts context-dependent drivers of myofibroblast differentiation. J Mol Cell Cardiol. 2016 May;94:72-81. doi: 10.1016/j.yjmcc.2016.03.008. Epub 2016 Mar 23. PubMed PMID: 27017945; PubMed Central PMCID: PMC4861657.
Adamson SE, Griffiths R, Moravec R, Senthivinayagam S, Montgomery G, Chen W, Han J, Sharma PR, Mullins GR, Gorski SA, Cooper JA, Kadl A, Enfield K, Braciale TJ, Harris TE, Leitinger N. Disabled homolog 2 controls macrophage phenotypic polarization and adipose tissue inflammation. J Clin Invest. 2016 Apr 1;126(4):1311-22. doi: 10.1172/JCI79590. Epub 2016 Feb 29. PMID: 26927671
Zeigler AC, Richardson WJ, Holmes JW, Saucerman JJ. Computational modeling of cardiac fibroblasts and fibrosis. J Mol Cell Cardiol. 2016 Apr;93:73-83. doi: 10.1016/j.yjmcc.2015.11.020. Epub 2015 Dec 1. Review. PubMed PMID: 26608708; PubMed Central PMCID: PMC4846515.
Lee CS, Penberthy KK, Wheeler KM, Juncadella IJ, Vandenabeele P, Lysiak JJ, Ravichandran KS. Boosting Apoptotic Cell Clearance by Colonic Epithelial Cells Attenuates Inflammation In Vivo. Immunity. 2016 Mar 28. pii: S1074-7613(16)30020-6. doi: 10.1016/j.immuni.2016.02.005. PMID: 27037190
Denno ME, Privman E, Borman RP, Wolin DC, Venton BJ. Quantification of Histamine and Carcinine in Drosophila melanogaster Tissues. ACS Chem Neurosci. 2016 Mar 16;7(3):407-14. doi: 10.1021/acschemneuro.5b00326. Epub 2016 Jan 28. PubMed PMID: 26765065; PubMed Central PMCID: PMC4798850
Gadani SP, Kipnis J. Shedding light on IL-33 in the eye. J Exp Med. 2016 Feb 8;213(2):141. doi: 10.1084/jem.2132insight2. PMID: 26858363
Ellwardt E, Walsh JT, Kipnis J, Zipp F. Understanding the Role of T Cells in CNS Homeostasis. Trends Immunol. 2016 Feb;37(2):154-65. doi: 10.1016/j.it.2015.12.008. Epub 2016 Jan 14. Review. PMID: 26775912
Reon BJ, Dutta A. Biological Processes Discovered by High-Throughput Sequencing. Am J Pathol. 2016 Jan 29. pii: S0002-9440(16)00006-7. doi: 10.1016/j.ajpath.2015.10.033. Review. PMID: 26828742
Gadani SP, Kipnis J. Natural killers in the brain’s nursery. Nat Neurosci. 2016 Jan 27;19(2):176-7. doi: 10.1038/nn.4227. PMID: 26814583
Penberthy KK, Ravichandran KS. Apoptotic cell recognition receptors and scavenger receptors. Immunol Rev. 2016 Jan;269(1):44-59. doi: 10.1111/imr.12376. Review. PMID: 26683144